The DEBUT study examined outcomes for patients with diverticulitis to better understand:

• how doctors and patients make decisions to have elective (non-emergency) surgery to remove all or part of the colon;

• how treatment decisions affect symptoms, quality of life, and overall health;

• the impact of diverticulitis on patients’ lives.

Results of this study are contributing to to the development of a patient-centered model of care for diverticulitis, informing patient and clinician decision-making, and laid the groundwork for current studies of treatments for diverticulitis, the COSMID and IMPEDE trials. 

Results

• Hantouli MN, Khor S, Strate L, Lavallee DC, Mower WR, Porter AJ, Flum DR, Davidson GH. What’s in a Number? Assessing the Burden of Diverticular Disease. Annals of Surgery Open 3(4):p e202, December 2022.

• Hantouli MN, Droullard DJ, Khor S, Strate LL, Lavallee DC, Flum DR, Davidson GH. Indications for surgical treatment of diverticulitis: factors that influence surgical decision-making for patients and surgeons. Br J Surg. 2022 Nov 22;109(12):1329-1330.

• Khor S, Flum DR, Strate LL, Hantouli MN, Harris HM, Lavallee DC, Spiegel BM, Davidson GH. Establishing Clinically Significant Patient-reported Outcomes for Diverticular Disease. J Surg Res. 2021 Aug;264:20-29.

• Thornblade LW, Simianu VV, Davidson GH, Flum DR. Elective Surgery for Diverticulitis and the Risk of Recurrence and Ostomy. Ann Surg. 2021 Jun 1;273(6):1157-1164.

• Thornblade LW, Flum DR, Flaxman AD. Predicting Future Elective Colon Resection for Diverticulitis Using Patterns of Health Care Utilization. EGEMS (Wash DC). 2018 Jan 24;6(1):1.

Funding

The DEBUT study was funded by the National Institute Of Diabetes And Digestive And Kidney Diseases under Award Number R01DK103915. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.